The Union Health Ministry said in a statement on Wednesday that facts have been “twisted and misrepresented” in some social media posts which suggested that indigenously developed Covaxin contains newborn calf serum.
Newborn calf serum is used only for the preparation and growth of vero cells.
It said, serum from bovine and other animal are standard enrichment ingredient used globally for vero cell growth. To establish the cell lines which help in the production of vaccines vero cells are used.
For developing vaccines against polio, rabies, and influenza this technique has been used for decades. The vero cells are washed in water and with chemicals after growth that is also technically known as buffer, multiple times to make them free from newborn calf serum. The vero cells are then infected with coronavirus for viral growth, said the health ministry.
It further said, the vero cells are completely destroyed in the process of viral growth. Thereafter, the grown virus is also killed (inactivated) and purified. Then the killed and inactivated virus is used to make the final vaccine, hence no calf serum is used in the formulation of the final vaccine, according to the statement.
“Hence, the final vaccine (Covaxin) does not contain newborn calf serum at all and the calf serum is not an ingredient of the final vaccine product.”