According to a study including data from about 200 hospitals around the US, complete vaccination against coronavirus is highly effective at preventing hospitalisation, emergency department visit, and intensive care admission due to infection with the virus.
The real-world evidence, published in the New England Journal of Medicine on Thursday, was gathered from electronic health records (EHRs) which demonstrate that the vaccines provide high levels of protection for populations disproportionately affected by the virus.
To create the VISION network to assess COVID-19 vaccine effectiveness the US Centers for Disease Control and Prevention (CDC) collaborated with six US healthcare systems plus the Regenstrief Institute.
The hospitalisation and ICU data for patients older than 50 years of age from a total of 187 hospitals, along in addition to data from emergency departments and urgent care clinics, has been contributed by all these institutes.
According to the data analysis it has been found that two-dose mRNA vaccination — Moderna and Pfizer — was 89 per cent effective at preventing COVID-19 hospitalisations, and 91 per cent effective at preventing emergency department or urgent care visits. The researchers said, the two-dose vaccination was 90 per cent effective at preventing COVID-19 intensive care unit admission.
The effectiveness was significantly lower in individuals who received only the first dose of the two shot-vaccination, they said.
Study lead author Mark Thompson, a member of the CDC COVID-19 Response Team said, “This study confirms that these vaccines are highly effective.”
“They offer significant protections for people older than 85, people with chronic medical conditions, as well as Black and Hispanic adults. All are groups who have been hit particularly hard by this disease,” Thompson said.
It is being hoped by the researchers that they hoped this finding will persuade more people to get vaccinated to protect not only themselves, but their community too.
The effectiveness of the single-dose Johnson and Johnson vaccine was looked after by the study. It was found to be 73 per cent effective against emergency department and urgent care visits, and 68 per cent against hospitalisations.
However, the authors of the study noted that the smaller sample size may affect the precision of these estimates and state that more data is needed.
“This real-world evidence corroborates the results of clinical trials and provides even more confidence in the vaccines,” said research paper author Shaun Grannis, a professor at the Indiana University School of Medicine, US.