Covaxin 50 Pc Effective Against Symptomatic COVID-19: Lancet Study

According to the first real-world examination of the coronavirus vaccine published in The Lancet Infectious Diseases journal, it has been found that two doses of COVID-19 vaccine Covaxin (BBV152) are 50 per cent effective against symptomatic COVID-19 disease.

According to the first real-world examination of the coronavirus vaccine published in The Lancet Infectious Diseases journal, it has been found that two doses of COVID-19 vaccine Covaxin (BBV152) are 50 per cent effective against symptomatic COVID-19 disease.

About 2,714 hospital workers at the All India Institute of Medical Sciences (AIIMS) in Delhi, from April 15-May 15, who were symptomatic were evaluated for the study and underwent RT-PCR test for coronavirus detection. “2714 symptomatic tested participants remained, of whom 1,617 tested positive for SARS-CoV-2 and 1,097 tested negative,” the study said.

“The unadjusted effectiveness of two doses of BBV152 against symptomatic RT-PCR-confirmed SARS-CoV-2, with an interval of at least 14 days between administration of the second dose and day of testing, was 53 per cent. After adjustment, the effectiveness was estimated to be 50 per cent. The adjusted effectiveness of two doses administered at least 28 days before testing was 46 per cent and administered at least 42 days before testing was 57 per cent,” it said.

Covaxin was approved for emergency use in India in the month of January for people aged 18 and above

The World Health Organization (WHO) added the vaccine to its list of approved emergency use coronavirus vaccines earlier this month.

Head of Medicine at AIIMS Delhi, Professor Naveet Wig said that the results demonstrate the effectiveness of BBV152 against symptomatic RT-PCR confirmed SARS-CoV-2 in the setting of a huge surge dominated by the delta variant.

“Given the long safety record and easy scalability of the platform on which it is developed, it is emerging as an important tool in the fight against COVID. It is important not to get fixated with varying effectiveness figures obtained from different studies under different conditions,” he said.

“Addressing vaccine hesitancy by the availability of a safe and effective vaccine and achieving universal coverage at a rapid pace are crucial to controlling the pandemic. Results also reinforce the need for continued adherence to non-pharmacological interventions like masks, social distancing and avoiding large public gatherings,” he said.

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